Table 1.

Summary of association results for all loci that passed replication criteria

Stratum	dbSNPID	CHR	POS (GRCh38)	Nearest gene	EAF	Other allele	Stage	EAF	Beta	SE	P	N
WHRadjBMI
AAb-combined	rs13301996	9	120 570 806	CDK5RAP2	T	G	SOL	0.8080	0.0050	0.0010	5.69E-07	12 672
							Replication	0.8720	0.0036	0.0014	1.10E-02	12 496
							SOL + replication	0.8295	0.0045	0.0008	2.88E-08	25 168
HLc−women	rs79478137	11	2 891 739	SLC22A18AS	T	C	SOL	0.0150	-0.0230	0.0040	2.03E-07	7472
							Replication	0.0169	-0.0116	0.0054	3.12E-02	6582
							SOL + replication	0.0157	-0.0189	0.0032	3.64E-09	14 054
WCadjBMI
EURd-combined	rs3168072	11	61 864 038	FADS2	A	T	SOL	0.7250	0.5140	0.1020	5.28E-07	12 674
							Replication	0.9750	2.0132	0.6323	1.45E-03	8845
							SOL + replication	0.7313	0.5520	0.1007	4.21E-08	21 519
HIPadjBMI
EURd-women	rs28692724e	14	77 027 445	IRF2BPL	T	C	SOL	0.4250	0.0020	0.0004	7.32E-07	7462
							Replication	0.303	0.789	0.305	9.62E-03	4678
							SOL + replication	0.3781	5.4900a		4.02E-08	12 140

EAF, estimated allele frequency; CHR, chromosome; pos, position; SE, standard error. Genome-wide significant (P<5×10⁻⁸) values are highlighted in bold.

^aFor rs28692724, SOL analyses were performed on log10-transformed HIP, while replication analyses in European descent population used untransformed hip measurements. In the SOL + replication analyses, an z-score is provided instead of a beta.

^bAA replication samples included: ARIC Study, Multi-Ethnic Study of Atherosclerosis (MESA) Study, Women’s Health Initiative (WHI) Study.

^cHispanic Latino (HL) replication samples included: Genetics of Latinos Diabetic Retinopathy (GOLDR), HCHS/SOL, Mexican–American Hypertension Study (HTN), MACAD, MESA, Mexico-City, 1982 Pelotas Birth Cohort (PELOTAS), Starr County Health Studies (STARR), WHI.

^dEuropean American (EA) replication samples included: ARIC.

^ers28692724 is <500 Kb from a previously reported SNP nominally associated with WHRadjBMI (PMID: 28552196).