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. 2021 Oct 21;22(6):847. doi: 10.3892/ol.2021.13108

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — METTL14 knockdown inhibits non-small cell lung cancer cell proliferation. (A) Interference efficiency of two different METTL14 siRNAs was detected in A549 and SK-MES-1 cells. (B) Proliferation of A549 and SK-MES-1 cells following METTL14 knockdown was determined using Cell Counting Kit-8 assays. (C) A colony formation assay was performed for 2 weeks in A549 and SK-MES-1 cells after knockdown of METTL14. Representative images (left) and the relative number of colonies (right) are shown. *P<0.05 and **P<0.01 vs. si-NC (one-way ANOVA with Tukey's post hoc test). METTL14/ME, methyltransferase-like 14; NC, negative control; OD, optical density; siRNA/si, small interfering RNA.