TABLE 4.
Substrate utilization results suggest that the model accurately captures phenotypic behavior of N. lanatia
| Substrate | Growthb |
|
|---|---|---|
| Model prediction | Exptl observation | |
| Carbon utilization | ||
| Glucose | + | + |
| Cellobiose | + | + |
| Sorbitol | + | − |
| Fructose | + | + |
| Galactose | + | − |
| Maltose | + | + |
| Mannose | + | − |
| Sucrose | + | + |
| Xylose | + | − |
| Arabinose | − | − |
| Rhamnose | − | − |
| Pyruvate | − | − |
| Succinate | − | − |
| Citrate | − | − |
| Glycerol | − | − |
| Pectin | − | − |
| Cellulose | + | + |
| Lignocellulose | + | + |
| Acetate | − | − |
| Fumarate | − | − |
| N-Acetyl-glucosamine | − | − |
| Lactate | − | − |
| Maltodextrin | + | + |
| Methanol | − | − |
| Oxaloacetate | − | − |
| Xylan | + | + |
| Ethanol | − | − |
| Malate | − | − |
| Formate | − | − |
| Raffinose | + | + |
| Phenylalanine | − | − |
| Arginine | − | − |
| Leucine | − | − |
| Proline | − | − |
| Serine | − | − |
| Threonine | − | − |
| Vitamin essentiality | ||
| Pyridoxine | + | + |
| p-Aminobenzoic acid | − | − |
| Biotin | − | + |
| Cyanocobalamin | + | + |
| Riboflavin | + | + |
| Folic acid | + | + |
| Pantothenate | + | + |
| Nicotinic acid | + | + |
| Thiamin | + | + |
| Heme | − | − |
a
The model accurately predicts phenotypic responses in 89% of the tested cases (Matthews correlation coefficient, 0.79). See Materials and Methods for details about the experiments that yielded these results.
b
+, the model predicted growth/there was experimentally observed growth; −, no predicted growth/no experimentally observed growth.