Table 4.
Examples of commercially available culture media for hiPSC expansion used in bioreactor settings
| Medium | Producer | Tested in bioreactor | References |
|---|---|---|---|
| mTeSR™1 | Stemcell Technologies (Vancouver, Canada) | Vertical-wheel impeller; hollow fiber; vertical paddle; rotating blade impeller; spinner flask | [15, 17, 18, 80, 90, 129] |
| TeSR™2 | Stemcell Technologies (Vancouver, Canada) | Spinner flask; vertical paddle | [70, 80] |
| TeSR™-E8™ | Stemcell Technologies (Vancouver, Canada) | Hollow fiber bioreactor | [19] |
| mTeSR™3D | Stemcell Technologies (Vancouver, Canada) | Vertical-wheel impeller | [18] |
| Essential 8™ | Thermo Fisher Scientific (Waltham, MA, USA) | Vertical-wheel impeller; rotating blade impeller; spinner flask | [15, 34, 126] |
| StemMACS iPS-Brew XF | Miltenyi (Bergisch Gladbach, Germany) | Spinner flask; rotating blade impeller | [17, 134] |
| StemPro™ | Thermo Fisher Scientific (Waltham, MA, USA) | Spinner flask | [135] |
| Cellartis DEF-CS Xeno-Free 3D Spheroid Culture Medium | Takara Bio Europe AB (Göteborg, Sweden) | Spinner flask | [16] |
hiPSCs human induced pluripotent stem cells