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. 2021 Nov 2;27(6):864–884. doi: 10.1007/s13365-021-01014-7

Fig. 1.

Fig. 1

Taxonomy of Coronaviridae based on the International Committee on Taxonomy of Viruses indicates species known to be pathogenic to humans. In a complicated evolutionary structure, changes in molecular virus genome empowered appearance and jumping from the first host to the intermediate host, and eventually to humans, the phenomenon called “spillover event” (Hussein et al. 2020)