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. 2021 Nov 2;27(6):864–884. doi: 10.1007/s13365-021-01014-7

Table 3.

Neuro-infection with SARS-CoV-2 in animals

Article/author Year of publication Type of animal Animal model Route of virus administration Duration of study Organs of involvement Neurological symptoms Non-neurological symptoms Mortality rate Suitable animal model
Lu et al. 2020

Old World monkey: Macaca mulatta, Macaca fascicularis

 + 

New World monkeys: Callithrix jacchus

Wild type

Old World monkeys: intratracheally + intranasally + on conjunctiva

New World monkeys: intranasally

21 days

Lung

Heart

Lymph node

Spleen

Liver

Kidney

Not mentioned Increased body temperature, weight loss, progressive pulmonary infiltration Not evaluated

Yes

M. mulatta is the most susceptible to SARS-CoV-2 infection as compared to M. fascicularis and C. jacchus