Table 1.
Demographic and Clinical Characteristics
| Characteristic | Patient Group (N = 21) | Healthy Controls (N = 10) | t/χ 2 | P |
|---|---|---|---|---|
| Gender (male/female) | 16/5 | 5/5 | 2.13 | 0.145 |
| Marital status (Mar/S) | 1/20 | 1/9 | 0.31 | 0.58 |
| Inpatient at baseline (Y/N) | 11/10 | |||
| Family Hx (Y/N/DN) | 10/6/5 | |||
| AP exposure at baseline (M/SD; days) | 2.95/3.11 | |||
| Total DDD-days at baseline scan (M/SD) | 2.25/4.74 | |||
| Total DDD-days at FUP scan (M/SD) | 145.68/97.56 | |||
| DUP (M/SD/median; wk) | 29.38/26.65/18 | |||
| Ethnicity (Black/White/Other) | 2/18/1 | 0/5/5 | 4.51 | 0.034a |
| Age (M/SD) | 22.33/5.29 | 21.60/3.37 | −0.47 | 0.645 |
| SOFAS at baseline scan (M/SD) | 42.33/12.84 | 83.70/5.62 | 12.47 | 0.000 |
| SOFAS at FUP scan (M/SD) | 61.25/9.85 | 85.10/3.21 | 9.83 | 0.000 |
| PANSS-8 total at baseline scan (M/SD) | 24.67/5.30 | |||
| PANSS-8 total at FUP scan (M/SD) | 14.35/4.77 | |||
| Smoker (yes/no) | 6/15 | 0/10 | 3.54 | 0.060 |
| Cannabis user (yes/no) | 13/8 | 0/10 | 10.66 | 0.001 |
| Time between scans (M/SD; mo) | 5.93/1.25 | 7.67/1.90 | 2.63 | 0.021 |
Note: Mar, married; S, single; Y, yes; N, no; Hx, history; DN, don’t know; AP, antipsychotic; M, mean; DDD, defined daily dose; FUP, follow-up; DUP, duration untreated psychosis. P values for differences between groups were calculated using chi-square analyses for categorical variables and independent t tests for continuous variables.
aWhite vs non-White comparison.