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. 2021 Oct 22;22(6):1473. doi: 10.3892/etm.2021.10908

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of TPs on the Mst-Nrf2 axis and Keap1/Nrf2/HO-1 pathway protein expression on RAW264.7 cells under oxidative damage. (A) The protein expression levels were tested using western blotting. (B) Keap1, (C) Mst2, (D) Mst1, (E) Nrf2 and (F) HO-1 proteins levels were quantified via densitometry and were normalized to β-actin. Each bar represents the mean ± SD of three independent experiments. ^*P<0.05 or ^**P<0.01 vs. the control group, ^##P<0.01 vs. the H₂O₂ group. TPs, tea polyphenols; Mst, mammalian STE20-like protein kinase; Nrf2, nuclear factor (erythroid-derived 2)-like 2; Keap1, Kelch-like ECH-associated protein 1; HO-1, heme oxygenase 1.