Table 2. Demographic and clinical details of the study group.
| Parameter | Total population ( n = 220) |
AKI group ( n = 161) |
No AKI group ( n = 59) |
p -Value |
|---|---|---|---|---|
| Age (mo) a | 33.1 ± 38.6 | 25.8 ± 34.7 | 53.2 ± 42.2 | 0.000 b |
| 1–24 | 137 (62.3) | 116 (72.0) | 21 (35.6) | 0.000 b |
| 25–60 | 37 (16.8) | 20 (12.4) | 17 (28.8) | |
| Above 60 | 46 (20.9) | 25 (15.5) | 21 (35.6) | |
| Male | 146 (66.4) | 105 (65.2) | 41 (69.5) | 0.552 |
| Female | 74 (33.6) | 56 (34.8) | 18 (30.5) | 0.630 |
| Available baseline creatinine | 103 (46.8) | 59 (36.7%) | 44 (74.6) | < 0.000 b |
| Baseline eCCl a (mL/min/1.73 m 2 ) | 86.3 ± 33.9 | 90.0 ± 34.8 | 76.1 ± 29.7 | 0.007 b |
| Comorbidities c | 93 (57.8) | 68 (42.2) | 25 (42.3) | 0.538 |
| PICU stay (d) a | 8.9 ± 13.9 | 9.1 ± 15.3 | 8.4 ± 9.4 | 0.742 |
| Hospital stay (d) a | 15.1 ± 15.3 | 14.7 ± 16.2 | 16.3 ± 12.7 | 0.478 |
| PICU stay > 5 d | 113 (51.4) | 85 (52.8) | 28 (47.5) | 0.109 |
| Hospital stay > 14 d | 88 (40) | 62 (38.5) | 26 (44.1) | 0.456 |
Abbreviations: AKI, acute kidney injury; eCCl, estimated creatinine clearance; PICU, pediatric intensive care unit.
Note: Numbers in parenthesis indicate percentages; continuous data are expressed as mean ± standard deviation.
a
Continuous variables for which statistical analysis was performed using unpaired t -test. The remaining categorical variables were analyzed using the chi-square test.
b
Statistically significant p -value.
c
Hematology/oncology: thalassemia major, aplastic anemia, intracranial space-occupying lesions and B – cell acute lymphocytic leukemia; cardiac: cyanotic and acyanotic congenital heart diseases; and Others: protein energy malnutrition, epilepsy and inborn errors of metabolism.