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. 2021 Nov 2;21:425. doi: 10.1186/s12883-021-02451-x

Table 1.

Study and patient characteristics – switching and discontinuation patterns among triptan users

Citation Country (Study period) Study type Study name/ database Sample Subgroup n Mean age, yrs % female
Alam, 2018 [35] US (2016) Multicenter cross-sectional, Survey MAST study Current users Overall 15,133 43.1 73.0
Chen, 2014 [36] Taiwan (2005-2008) Database study NHIR Database Incident users Overall 13,951 41.3 77.0
Fischer, 2016 [37] Austria (2009-2012) Single center chart review Outpatient clinic, U of Innsbruck Incident users (first/new agent) Overall 126 37.2 88.1
Katic, 2011 [38] US (2001-2005) Database study i3 InVision Data Mart Incident users Overall 40,892 37.8 78.9
Lombard, 2018 [39] US (2012-2014) Database study Truven MarketScan Incident users Overall 124,556 30.0-49.0 81.0
Ng-Mak, 2012 [40] EU (2006-2008) Database study IMS Disease Analyzer Incident users UK 3618 41.3 75.6
France 2051 38.9 75.8
Germany 954 41.6 78.0
Serrano, 2013 [41] US (2005-2009) Multicenter prospective, Survey AMPP study Current users Consistency group A 700 47.3 89.0
Consistency group B 697 47.2 88.5
Consistency group C 687 47.1 88.6

Consistency group A: Did not switch to another triptan in any couplet and consistently used the same triptan across years in their first eligible couplet; Consistency group B: Did not switch to an opioid/ barbiturate in any couplet and consistently used the same triptan across years in their first eligible couplet; Consistency group C: Did not switch to an NSAID in any couplet and consistently used the same triptan across years in their first eligible couplet

Abbreviations: AMPP American Migraine Prevalence and Prevention, EU Europe, IMS Information Management System, MAST Migraine in America Symptoms and Treatment, NHIR National Health Insurance Research, SC Subcutaneous inj., U University, US United States, Yrs Years