Table 2.
Study and patient characteristics – medication overuse headache among triptan users
| Citation | Country (Study period) | Study type | Sample (MOH care setting, treatment) | n, MOH | % previous history migraine | Headache criteria | MHD | Mean age, yrs | % female |
|---|---|---|---|---|---|---|---|---|---|
| Benz et al., 2017 [42] | Switzerland (2012, 2014) | Single center cross-sectional, survey | Inpatient and outpatient, withdrawal of acute medication, prophylaxis | 51 | 90.0 | ICHD-II beta | NR | 47.3 | 72.5 |
| Chagas, 2015 [43] | Brazil (2009, 2010) | Single center prospective, survey | Outpatient, NR | 29 | 100 | ICHD-II | NR | 44.2 | 82.8 |
| Creac’h et al., 2009 [44] | France (2004, 2006) | Multicenter cross-sectional, survey | Inpatient, withdrawal of acute medication, prophylaxis; all overused triptans | 163 | 99.0 | ICHD-II | 26.0 | 50.0 | 85.0 |
| de Rijk et al., 2018 [45] | France (2006, 2015) | Single center, chart review | Inpatient, withdrawal of acute medication; > 65 years | 79 | 100 | ICHD-II beta | NR | 69.5 | 79.1 |
| Grande et al., 2011 [46] | Norway (2005, 2008) | Single center prospective, survey | Inpatient, education about medication overuse, prophylaxis | 109 | 8.0 | ICHD-II | 22.0 | 37.5 | 30.3 |
| Imai et al., 2007 [47] | Japan (NR) | Single center chart review | Inpatient and outpatient, withdrawal of acute medication | 47 | 90.0 | ICHD-II | NR | NR | NR |
| Katsarava et al., 2003a [48] | Germany (NR) | Single center prospective cohort | Outpatient, withdrawal of acute medication | 96 | 71.0 | ICHD-I | NR | 43.0 | 81.0 |
| Kluonaitis et al., 2017 [49] | Lithuania (2015, 2016) | Single center chart review | Outpatient, likely withdrawal of acute medication, patients on prophylactic medication were excluded | 87 | 67.0 | ICHD-II beta | 24.1 | 43.8 | 90.8 |
| Lake et al., 2009 [50] | US and Canada (NR) | Single center chart review | Inpatient, withdrawal from acute mediation, prophylaxis, cognitive-behavioral therapy | 158 | 85.0 | ICHD-II | NR | 40.0 | 79.4 |
| Limmroth et al., 2002a [51] | Germany (NR) | Single center prospective cohort | Outpatient, withdrawal of acute medication | 96 | 71.0 | ICHD-I | NR | 43.0 | 81.0 |
| Radat et al., 2005 [52] | France (NR) | Single center cross-sectional, survey | Inpatient, withdrawal of acute medication | 41 | 100 | ICHD-II | 27.0 | NR | NR |
| Zeeberg et al., 2006 [53] | Denmark (2002, 2003) | Single center prospective cohort | Outpatient, withdrawal of acute medication | 216 | 53.0 | ICHD-II | 17.0 | 48.0 | 73.0 |
| Zidverc-Trajkovic et al, 2007 [54] | Serbia (2000, 2005) | Single center prospective cohort | Inpatient, prophylaxis | 240 | 67.1 | ICHD-II | 24.0 | 41.5 | 75.8 |
Abbreviations: ICHD The International Classification of Headache Disorders, MOH Medication overuse headache, MHD Monthly headache days, NR Not reported, US United States, Yrs Years
aSame patient population, different outcomes