Table 3.

Possible determinants affecting increment of CAC percentiles in breast cancer patients

Variables	β (95% CI)	p value
Laterality of disease
Right-side BC	Ref	Ref
Left-side BC	15.13 (2.37, 27.87)	0.020
Pathology stage
I	Ref	Ref
II	− 10.46 (− 30.09–9.17)	0.296
III	− 5.71 (− 23.90–12.49)	0.539
IV	− 17.07 (− 51.09–17.46)	0.333
Pathology stage
0 vs. I vs. II	Ref	Ref
III vs. IV	0.215 (− 12.90, 13.33)	0.974
Surgery
Mastectomy	Ref	Ref
BCS	− 3.08 (− 16.85, 10.70)	0.659
Chemotherapy
No	Ref	Ref
Yes	− 6.94 (− 23.86, 9.98)	0.417
Hormone therapy
No	Ref	Ref
Yes	− 2.10 (− 17.29, 13.10)	0.785
Targeted therapy
No	Ref	Ref
Yes	− 6.10 (− 35.19, 22.10)	0.678
Overweight
BMI < 24	Ref	Ref
BMI ≧ 24	− 6.19 (− 19.21, 6.83)	0.347
Obese
BMI < 27	Ref	Ref
BMI ≧ 27	1.18 (− 13.61, 15.97)	0.874
Diabetes
No	Ref	Ref
Yes	13.99 (− 3.62, 31.60)	0.118
Hypertension
No	Ref	Ref
Yes	1.62 (− 14.34, 17.59)	0.841
Hyperlipidemia
No	Ref	Ref
Yes	− 1.59 (− 20.52, 17.34)	0.867
Total irradiation dose (Gy)	− 0.37 (− 1.32, 0.58)	0.439

CAC coronary artery calcium, BC breast cancer, BCS breast-conserving surgery, BMI body mass index, Gy gray

Significant p value was in bold