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. 2021 Nov 1;21:524. doi: 10.1186/s12872-021-02327-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — a The heart function index was detected by left ventriculography. A 4f catheter was used according to the operation standard. The detection items included: left ventricular ejection fraction (LVEF), left ventricular short-axis shortening rate (LVFS), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD). b The BNP level in serum was detected by ELISA, 5 ml of peripheral venous blood was extracted before and after treatment, respectively, and the BNP level was detected by enzyme-linked immunosorbent assay. c 1 × 104 cells were inoculated into a 6-well plate and cultured in a 5% CO₂ incubator at 37 °C for 2 weeks. Crystal violet dye was added, and the number of clones was counted. d. The statistical analysis of clone number (*P < 0.05)