Table 3.
Effects of polyphenol rich extract of Ocimum gratissimum leaves on water intake, urine output, food consumption (g) and body weight (g) in cyclophosphamide-treated rats
Baseline | 24 h. after 7 days of administration of drugs | |
---|---|---|
Water Intake (ml/24 h) | ||
[1] Control | 17.70 ± 0.40 | 18.70 ± 0.59 |
[2] PREOG 400 mg/kg | 15.70 ± 0.73 | 19.60 ± 0.43 |
[3] CP (50 mg/kg) | 18.30 ± 1.69 | 30.80 ± 1.33* |
[4] PREOG 400 mg/kg + CP | 15.90 ± 1.76 | 20.10 ± 1.66# |
Urine Output (ml/24 h.) | ||
[1] Control | 12.60 ± 0.21 | 13.10 ± 0.19 |
[2] PREOG (400 mg/kg) | 13.10 ± 0.35 | 14.60 ± 0.33 |
[3] CP (50 mg/kg) | 14.00 ± 1.39 | 20.85 ± 1.03* |
[4] PREOG (400 mg/kg) + CP | 14.11 ± 1.44 | 16.00 ± 1.46# |
Food consumption (g) | ||
[1] Control | 11.60 ± 0.80 | 15.80 ± 0.13 |
[2] PREOG (400 mg/kg) | 14.80 ± 0.43 | 20.60 ± 0.33 |
[3] CP (50 mg/kg) | 12.80 ± 1.29 | 10.06 ± 1.03* |
[4] PREOG (400 mg/kg) + CP | 12.20 ± 1.42 | 14.50 ± 1.06# |
Body weight (g) | ||
[1] Control | 135.40 ± 3.37 | 150.00 ± 2.44 |
[2] PREOG (400 mg/kg) | 150.00 ± 1.75 | 170.20 ± 4.00 |
[3] CP (50 mg/kg) | 145.20 ± 4.89 | 129.10 ± 2.01* |
[4] PREOG (400 mg/kg) + CP | 150.60 ± 6.47 | 146.40 ± 3.16# |
Each value represents mean ± SEM (n = 7). * (p < 0.05) = significantly different from control in the same column. # (p < 0.05) = significantly different from CP (50 mg/kg) in the same column