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. 2021 Nov 2;21:274. doi: 10.1186/s12906-021-03447-3

Table 3.

Effects of polyphenol rich extract of Ocimum gratissimum leaves on water intake, urine output, food consumption (g) and body weight (g) in cyclophosphamide-treated rats

Baseline 24 h. after 7 days of administration of drugs
Water Intake (ml/24 h)
 [1] Control 17.70 ± 0.40 18.70 ± 0.59
 [2] PREOG 400 mg/kg 15.70 ± 0.73 19.60 ± 0.43
 [3] CP (50 mg/kg) 18.30 ± 1.69 30.80 ± 1.33*
 [4] PREOG 400 mg/kg + CP 15.90 ± 1.76 20.10 ± 1.66#
Urine Output (ml/24 h.)
 [1] Control 12.60 ± 0.21 13.10 ± 0.19
 [2] PREOG (400 mg/kg) 13.10 ± 0.35 14.60 ± 0.33
 [3] CP (50 mg/kg) 14.00 ± 1.39 20.85 ± 1.03*
 [4] PREOG (400 mg/kg) + CP 14.11 ± 1.44 16.00 ± 1.46#
Food consumption (g)
 [1] Control 11.60 ± 0.80 15.80 ± 0.13
 [2] PREOG (400 mg/kg) 14.80 ± 0.43 20.60 ± 0.33
 [3] CP (50 mg/kg) 12.80 ± 1.29 10.06 ± 1.03*
 [4] PREOG (400 mg/kg) + CP 12.20 ± 1.42 14.50 ± 1.06#
Body weight (g)
 [1] Control 135.40 ± 3.37 150.00 ± 2.44
 [2] PREOG (400 mg/kg) 150.00 ± 1.75 170.20 ± 4.00
 [3] CP (50 mg/kg) 145.20 ± 4.89 129.10 ± 2.01*
 [4] PREOG (400 mg/kg) + CP 150.60 ± 6.47 146.40 ± 3.16#

Each value represents mean ± SEM (n = 7). * (p < 0.05) = significantly different from control in the same column. # (p < 0.05) = significantly different from CP (50 mg/kg) in the same column