Table 4.

Effects of polyphenol rich extract of Ocimum gratissimum leaves on some parameter of renal function in cyclophosphamide-treated rats

Creatinine Concentration	Plasma Level	Urine Level
Groups	(μmol/L)	(μmol/L)
[1] Control	34.48 ± 4.33	1768.4 ± 5.56
[2] PREOG (400 mg/kg)	39.79 ± 2.38	1945.24 ± 8.65
[3] CP (50 mg/kg)	168.00 ± 3.23*	970.85 ± 4.33*
[4] PREOG (400 mg/kg) + CP	44.21 ± 4.57#	1670.25 ± 6.45#
Urea Concentration	Plasma Level	Urine Level
Groups	(mmol/L)	(mmol/L)
[1] Control	5.90 ± 0.27	200.02 ± 21.39
[2] PREOG (400 mg/kg)	7.00 ± 0.92	200.90 ± 15.88
[3] CP (50 mg/kg)	16.70 ± 5.26*	130.03 ± 20.19*
[4] PREOG (400 mg/kg) + CP	11.95 ± 0.42*#	179.67 ± 30.38#
Cystatin C Concentration	Plasma Level	Urine Level
Groups	(ng/ml)	(ng/ml)
[1] Control	0.23 ± 0.31	12.34 ± 3.01
[2] PREOG (400 mg/kg)	0.25 ± 0.44	13.30 ± 2.08
[3] CP (50 mg/kg)	0.59 ± 0.66*	25.34 ± 1.19*
[4] PREOG (400 mg/kg) + CP	0.43 ± 0.23#	15.08 ± 1.38#
Albumin	Plasma Level	Urine Level
Groups	(g/dl)	(mg/dl)
[1] Control	6.44 ± 0.55	0.19 ± 0.71
[2] PREOG (400 mg/kg)	7.09 ± 0.21	0.22 ± 1.01
[3] CP (50 mg/kg)	3.22 ± 0.25*	1.25 ± 0.91*
[4] PREOG (400 mg/kg) + CP	5.78 ± 1.01#	0.28 ± 0.08#
Albumin/Creatinine Ratio	(mg/g)
Groups
[1] Control	9.91 ± 0.51
[2] PREOG (400 mg/kg)	10.70 ± 1.32
[3] CP (50 mg/kg)	113.8 ± 4.66*
[4] PREOG (400 mg/kg) + CP	14.80 ± 0.52#

Each value represents mean ± SEM (n = 7). * (p < 0.05) = significantly different from control in the same column. ^# (p < 0.05) = significantly different from CP (50 mg/kg) in the same column