Table 1.
Baseline Characteristics and Laboratory Values for Patients With SARS-CoV-2
| Variable | Mortality or Hospice Care | Discharged Alive | P Value |
|---|---|---|---|
| Total No. | 121 | 511 | ... |
| Age, y | 72 (64-81) | 60 (45-71) | < .001 |
| Male sex | 69 (57) | 225 (44) | .013 |
| Black race | 35 (29) | 163 (32) | .6 |
| Nursing home resident | 44 (36) | 70 (14) | < .001 |
| BMI, kg/m2 | .459 | ||
| < 18 | 3 (2) | 9 (2) | |
| 18-24.9 | 36 (30) | 113 (22) | |
| 25-29.9 | 28 (23) | 128 (25) | |
| 30-34.9 | 27 (22) | 111 (22) | |
| 35-39.9 | 12 (10) | 62 (12) | |
| > 40 | 15 (12) | 88 (17) | |
| Vital signs | |||
| Heart rate | 92 (81-112) | 98 (82-110) | .542 |
| SBP < 90 mm Hg or DBP < 60 mm Hg | 63 (52) | 146 (29) | < .001 |
| Respiratory rate ≥ 30 breaths/min | 41 (34) | 75 (15) | < .001 |
| Temperature < 95 °F (35 °C) | 1 (1) | 2 (0) | > .999 |
| Temperature ≥ 100.4 °F (38 °C) | 52 (43) | 214 (42) | .907 |
| Medical history | |||
| Any comorbidity | 108 (89) | 368 (72) | < .001 |
| > 2 comorbidities | 64 (53) | 122 (24) | < .001 |
| COPD | 29 (24) | 67 (13) | .004 |
| Asthma | 6 (5) | 61 (12) | .038 |
| Obstructive sleep disorder | 14 (12) | 46 (9) | .488 |
| Diabetes | 58 (48) | 156 (31) | < .001 |
| Heart failure | 40 (33) | 59 (12) | < .001 |
| Hypertension | 88 (73) | 264 (52) | < .001 |
| Stroke | 31 (26) | 55 (11) | < .001 |
| Neoplastic disease within past year | 19 (16) | 26 (5) | < .001 |
| Renal disease | 39 (32) | 80 (16) | < .001 |
| Cirrhosis | 2 (2) | 6 (1) | > .999 |
| Current smoker | 13 (11) | 45 (9) | .625 |
| Former smoker | 40 (33) | 130 (25) | .113 |
| Laboratory results on admission | |||
| Lymphocyte count, cells/mm3 | 0.80 (0.56-1.23) | 1.08 (0.73-1.47) | < .001 |
| Neutrophil count, cells/mm3 | 6.38 (3.34-11.45) | 4.40 (2.99-6.72) | < .001 |
| Neutrophil to lymphocyte ratio | 6.38 (3.49-14.50) | 4.05 (2.63-6.77) | < .001 |
| Platelets, cells/mm3 | 173 (126-226) | 198 (163-251) | < .001 |
| Ferritin, ng/mLa | 525 (213-1,181) | 377 (166-814) | .027 |
| D-dimer, μg/mLb | 1,309 (676-2,772) | 691 (372-1,296) | < .001 |
| CRP, mg/Lc | 18 (7-40) | 14 (5-34) | .052 |
| ESR, mm/hd | 51 (32-99) | 51 (32-74) | .399 |
| Procalcitonin, ng/mLe | 0.48 (0.12-1.40) | 0.10 (0.05-0.27) | < .001 |
| Initial serum troponin, ng/mLf | 0.03 (0.01-0.08) | 0.01 (0.01-0.03) | < .001 |
| Lactate dehydrogenase, units/Lg | 625.0 (319-974) | 451.5 (251.75-731.75) | .001 |
| pHh | 7.40 (7.32-7.45) | 7.44 (7.40-7.47) | < .001 |
| Pao2 to Fio2 ratio, %i | .005 | ||
| > 300 | 25 (31) | 60 (38) | |
| 200-300 | 13 (16) | 45 (28) | |
| 100-199 | 18 (22) | 33 (21) | |
| < 100 | 24 (30) | 20 (13) |
Data are presented as No. (%) or median (interquartile range), unless otherwise indicated. For all data points, < 1% are missing, except as noted. CRP = C-reactive protein; DBP = diastolic BP; ESR = erythrocyte sedimentation rate; SBP = systolic BP.
Data missing for 30 mortality or hospice care patients (25%) and 167 patients discharged alive (33%).
Data missing for 31 mortality or hospice care patients (26%) and 154 patients discharged alive (30%).
Data missing for 38 mortality or hospice care patients (31%) and 158 patients discharged alive (31%).
Data missing for 88 mortality or hospice care patients (73%) and 412 patients discharged alive (81%).
Data missing for 20 mortality or hospice care patients (17%) and 108 patients discharged alive (21%).
Data missing for 27 mortality or hospice care patients (22%) and 161 patients discharged alive (32%).
Data missing for 35 mortality or hospice care patients (34%) and 175 patients discharged alive (29%).
Data missing for 41 mortality or hospice care patients (34%) and 353 patients discharged alive (69%).
Data missing for 41 mortality or hospice care patients (34%) and 353 patients discharged alive (69%).