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. 2021 Nov 2;161(4):927–936. doi: 10.1016/j.chest.2021.10.031

Table 2.

ROC Analysis for PSI and CURB-65 Score in Patients With SARS-CoV-2 CAP and Non-SARS-CoV-2 CAP

Variable Patient Population AUC (95% CI) Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI)
PSI Non-SARS-CoV-2 CAP 0.79 (0.77-0.80) 0.71 (0.67-0.75) 0.78 (0.77-0.79) 0.16 (0.15-0.18) 0.98 (0.97-0.98)
SARS-CoV-2 CAP 0.82 (0.78-0.86) 0.83 (0.55-0.91) 0.66 (0.61-0.92) 0.37 (0.31-0.61) 0.94 (0.90-0.97)
CURB-65 score Non-SARS-CoV-2 CAP 0.75 (0.73-0.77) 0.72 (0.68-0.77) 0.66 (0.65-0.67) 0.12 (0.10-0.13) 0.97 (0.97-0.98)
SARS-CoV-2 CAP 0.79 (0.75-0.84) 0.83 (0.50-0.89) 0.61 (0.58-0.85) 0.33 (0.29-0.52) 0.94 (0.89-0.96)

The 95% CI is calculated from the 2.5 and 97.5 percentiles of the bootstrap distribution. AUC = area under the receiver operating characteristic curve; CAP = community-acquired pneumonia; CURB-65 = Confusion, Urea > 7 mM, Respiratory Rate ≥ 30 breaths/min, BP < 90 mm Hg (Systolic) or < 60 mm Hg (Diastolic), Age ≥ 65 Years; NPV = negative predictive value; PPV = positive predictive value; PSI = Pneumonia Severity Index;. ROC = receiver operating characteristic.