Table 2.
ROC Analysis for PSI and CURB-65 Score in Patients With SARS-CoV-2 CAP and Non-SARS-CoV-2 CAP
| Variable | Patient Population | AUC (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) |
|---|---|---|---|---|---|---|
| PSI | Non-SARS-CoV-2 CAP | 0.79 (0.77-0.80) | 0.71 (0.67-0.75) | 0.78 (0.77-0.79) | 0.16 (0.15-0.18) | 0.98 (0.97-0.98) |
| SARS-CoV-2 CAP | 0.82 (0.78-0.86) | 0.83 (0.55-0.91) | 0.66 (0.61-0.92) | 0.37 (0.31-0.61) | 0.94 (0.90-0.97) | |
| CURB-65 score | Non-SARS-CoV-2 CAP | 0.75 (0.73-0.77) | 0.72 (0.68-0.77) | 0.66 (0.65-0.67) | 0.12 (0.10-0.13) | 0.97 (0.97-0.98) |
| SARS-CoV-2 CAP | 0.79 (0.75-0.84) | 0.83 (0.50-0.89) | 0.61 (0.58-0.85) | 0.33 (0.29-0.52) | 0.94 (0.89-0.96) |
The 95% CI is calculated from the 2.5 and 97.5 percentiles of the bootstrap distribution. AUC = area under the receiver operating characteristic curve; CAP = community-acquired pneumonia; CURB-65 = Confusion, Urea > 7 mM, Respiratory Rate ≥ 30 breaths/min, BP < 90 mm Hg (Systolic) or < 60 mm Hg (Diastolic), Age ≥ 65 Years; NPV = negative predictive value; PPV = positive predictive value; PSI = Pneumonia Severity Index;. ROC = receiver operating characteristic.