Skip to main content
. 2021 Nov 2;26(11):6209–6217. doi: 10.1038/s41380-021-01335-3

Fig. 5. Phenome-wide (top) and lab-wide (bottom) association studies of polygenic risk scores for POU against 1,338 diseases and 315 biomarkers (respectively) available from BioVU.

Fig. 5

The top and bottom red dashed lines indicate the threshold for Bonferroni correction (PheWAS p = 3.74E–05; LabWAS p = 1.59E–04). Only FDR significant results are presented. The sizes of the dots correspond to the magnitude of the effect. Y-axis represents the negative logarithm of the p-value for each trait multiplied by the sign of the effect.