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. 2021 Nov 2;15(1):116–122. doi: 10.1016/j.jiph.2021.10.024

Table 1.

Baseline characteristics determined for the study population (no, %).

Item TCZ-HCQ (n = 56) TCZ-RMV (n = 52) P-value
Age, yr. 53(46−68) 61(52−70) 0.015
Gender, male (%) 45(80.4%) 32(61.5%) 0.03
Oxygen saturation% 85(69−89) 82(75−88) 0.4
Respiratory rate 29(23−31.8) 30(25−33) 0.15
Max temperature, celsius 39(38−39) 38(37.5−39) 0.05
Serum creatinine 1.2(1.1−1.6) 1.4(1.2−2) 0.041
Comorbidities
Hypertension, no. (%) 37(66.1%) 29(55.8%) 0.27
Diabetes, no. (%) 26(46.4%) 25(48.1%) 0.86
Ischemic heart disease, no. (%) 16(28.6%) 7(13.5%) 0.06
Heart failure, no. (%) 3(5.4%) 1(1.9%) 0.35
Atrial fibrillation, no. (%) 5(8.9%) 1(1.9%) 0.11
Chronic kidney disease, no. (%) 2(3.6%) 3(5.8%) 0.59
Asthma, no. (%) 10(17.9%) 4(7.7%) 0.12
Chronic obstructive pulmonary disease, no. (%) 2(3.6%) 1(1.9%) 0.6
2 or more comorbidities, no. (%) 30(53.6%) 26(50%) 0.43
Respiratory support
Supplemental oxygen at entry, no. (%) 49(87.5%) 9(17.3%) <0.001
Mechanical ventilation need, no. (%) 25(44.6%) 43(82.7%) <0.001
ICU admission, no. (%) 44(78.6%) 50(96.2%) 0.007

Data are expressed as median IQR.