FIG. 4.

M-CSF induces expression of the macrophage scavenger receptor in Hoxa9-immortalized promyelocytes. Shown is Western blot detection of the macrophage-specific scavenger receptor in promyelocytes immortalized by Hoxa9 (clone HF1 [lanes 2 to 4], subclone HF1.1 [lanes 5 to 7], and subclone HF1.2 [lanes 8 to 10]), Hoxa9-WF (clone 1; lanes 11 to 13), Hoxa9-Atet (lanes 14 to 16), and Hoxa9-Gtet (lanes 17 to 19), each grown in GM-CSF (lanes 2, 5, 8, 11, 14, and 17), G-CSF for 72 h lanes 3, 6, 9, 12, 15, and 18), or M-CSF for 120 h (lanes 4, 7, 10, 13, 16, and 19). Lane 1, mouse peritoneal macrophages (as a positive control).