Table 2.
Results of univariate and multivariate analyses.
| Clinical characteristics | Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| HR (95% CI) | p-Value | HR (95% CI) | p-Value | |
| Sex | ||||
| Male | 0.975 | 0.961 | NA | NA |
| Female | 0.351–2.709 | |||
| Age (years) | ||||
| <65 | 1.155 | 0.614 | NA | NA |
| ≥65 | 0.659–2.023 | |||
| Child-Pugh classification | ||||
| A | 5.196 | <0.001 | 4.656 | <0.001 |
| B | 2.724–9.911 | 2.333–9.291 | ||
| Serum AFP (ng/mL) | ||||
| <400 | 1.886 | 0.010 | 2.173 | 0.002 |
| ≥400 | 1.167–3.048 | 1.326–3.560 | ||
| ECOG-PS | ||||
| 0–1 | 4.384 | <0.001 | 3.719 | <0.001 |
| 2 | 2.523–7.616 | 2.086–6.628 | ||
| Recurrence after surgical resection | ||||
| No | 1.304 | 0.459 | NA | NA |
| Yes | 0.646–2.630 | |||
| Tumor size (cm) | ||||
| <5.0 | 2.055 | 0.023 | 1.408 | 0.294 |
| ≥5 | 1.106–3.819 | 0.743–2.669 | ||
| No. of tumors | ||||
| <3 | 1.193 | 0.465 | NA | NA |
| ≥3 | 0.743–1.915 | |||
HR: hazard ratio; CI: confidence interval; MVI: microvascular invasion; EHM: extrahepatic metastases; AFP: alpha fetoprotein; ECOG-PS: Eastern Cooperative Oncology Group performance status; NA: not applicable.
Bold indicates that the data is statistically significant.