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Observed toxicity according to the CTCAE.
| Severity grade | Value | ||
|---|---|---|---|
| Hematological | |||
| Thrombocytopenia | 2–3 | 7 (18.9%) | |
| Neutropenia | 3–4 | 0 (0.0%) | |
| Non-hematological | |||
| Elevation of liver enzymes | 3–4 | 8 (21.6%) | |
| Elevation of bilirubin | 1–2 | 28 (75.7%) | |
| Nausea/vomiting | 1–2 | 18 (48.6%) | |
| Pain | 1–2 | 12 (32.4%) | |
| Fever | 1 | 14 (37.8%) | |
Toxicity was assessed according to the CTCAE v.4.0 criteria. CTCAE, Common Terminology Criteria for Adverse Events.
