Table 4.
Univariate and multivariate analyses of predictors of overall survival.
| Characteristic | Univariate (p*-value) | Multivariate (p*-value) | HR | 95% CI |
|---|---|---|---|---|
| Age (≤65 y) | 0.276 | |||
| Sex | 0.395 | |||
| Diameter (≤50 mm) | 0.028 | |||
| Child–Pugh stage | 0.789 | |||
| BCLC | 0.012 | 0.029 | 3.080 | 1.122–8.455 |
| ECOG performance status | 0.183 | |||
| Tumor nodules | 0.159 | |||
| Vascular invasion | 0.064 | |||
| HBV DNA level >2 × 103 copies/mL | 0.033 | |||
| Cirrhosis | 0.759 | |||
| AFP | 0.544 | |||
| dNLRa ≤2 | 0.003 | 0.004 | 0.020 | 0.064–0.599 |
AFP, alpha-fetoprotein; BCLC, Barcelona Clinic Liver Cancer; ECOG, Eastern Cooperative Oncology Group; HBV, hepatitis B virus; dNLR, derived neutrophil-to-leukocyte ratio; HR, hazard ratio; CI, confidence interval.
a
dNLR = leukocyte/(absolute leukocyte count - absolute neutrophil count); * < 0.05.