Table 2.
Results of meta-analyses comparing the diagnostic accuracy of HUD with first-line TTE
| HUD compared with TTE | |||||||||
| Sensitivity % | Total | Experienced | Inexperienced | ||||||
| Studies (n) | Prevalence | Sensitivity (95% CI) | Studies (n) | Prevalence | Sensitivity (95% CI) | Studies (n) | Prevalence | Sensitivity (95% CI) | |
| LVEF (any abnormality) | 15 (2936) | 0.23 | 86 (80 to 90) | 9 (1406) | 0.18 | 88 (81 to 92) | 9 (1530) | 0.28 | 83 (71 to 90) |
| LVEF (moderate/severe) | 10 (1611) | 0.27 | 91 (86 to 94) | 5 (722) | 0.27 | 93 (89 to 96) | 7 (889) | 0.27 | 84 (72 to 92) |
| WMA | 13 (1931) | 0.27 | 81 (74 to 85) | 6 (794) | 0.26 | 85 (76 to 91) | 7 (1137) | 0.28 | 78 (70 to 84) |
| LV dilatation | 10 (1966) | 0.13 | 73 (59 to 84) | 6 (966) | 0.17 | 89 (64 to 97) | 6 (1000) | 0.09 | 68 (51 to 81) |
| LVH | 12 (2229) | 0.24 | 83 (73 to 90) | 6 (1096) | 0.23 | 85 (72 to 92) | 7 (1133) | 0.26 | 80 (61 to 91) |
| LVEF (any abnormality) | 14 (2851) | 0.21 | 91 (87 to 95) | 8 (1368) | 0.16 | 96 (90 to 98) | 8 (1483) | 0.26 | 89 (81 to 93) |
| LVEF (moderate/severe) | 10 (1611) | 0.27 | 92 (87 to 96) | 5 (722) | 0.27 | 96 (87 to 99) | 7 (889) | 0.27 | 91 (83 to 95) |
| WMA | 12 (1876) | 0.28 | 90 (88 to 92) | 6 (759) | 0.27 | 95 (93 to 96) | 6 (1117) | 0.28 | 88 (85 to 90) |
| LV dilatation | 10 (1966) | 0.13 | 95 (94 to 97) | 6 (966) | 0.17 | 98 (93 to 99) | 6 (1000) | 0.09 | 95 (93 to 96) |
| LVH | 11 (2228) | 0.25 | 90 (82 to 95) | 5 (1095) | 0.23 | 91 (82 to 96) | 7 (1133) | 0.26 | 87 (67 to 96) |
HUD, handheld ultrasound devices; LV, left ventricular; LVEF, LV ejection fraction; LVH, LV dilatation and hypertrophy; TTE, transthoracic echocardiography; WMA, wall motion abnormalities.