Figure 3.

Associations of genetic proxies for cardiometabolic traits with current night-shift work patterns¹. The plotted estimates correspond to a unit change in the GRS, or to an additional effect allele for the single-SNP instruments. All effects are oriented to an increase in the exposure, except for educational attainment which is oriented to lower levels of educational attainment. n_controls = 159 903, n_{shifts but no nights} = 15 288, n_{some nights} = 8726, n_{frequent nights}=6629. BMI, body mass index; CAD, coronary artery disease; CI, confidence interval; GRS, genetic risk score; SNP, single nucleotide polymorphism; DM, diabetes mellitus; OR, odds ratio; WHRadjBMI, waist-to-hip ratio adjusted for BMI