Figure 8.

Synthesis and bioactivity of liposomes surface conjugated with anti-CD137 antibody or IL2-Fc fusion protein. (A) schematic for synthesis of liposomes. (B) Flow cytometry of CD4⁺ and CD8⁺ T cells incubated with fluorescently-labeled liposomes (solid), unconjugated liposomes (dashed), or no liposomes (grey area). (C) In vitro T cell proliferation normalized to unstimulated cells. (D) IFN-γ production by polyclonal T cells. Reproduced with permission.^[233] Copyright 2013, American Association for Cancer Research.