Skip to main content
. 2021 Sep 9;8(Pt 6):878–895. doi: 10.1107/S2052252521008125

Table 2. Parameters for the mix-and-inject experiments.

Concentrations of ceftriaxone (CEF) and sulbactam (SUB) are shown as were flowed through the outer capillary line of the mixing injectors. Time delays are achieved after mixing in a constriction as per Calvey et al. (2019).

  Water SUB CEF CEF CEF
Δt m (ms) (10) 66 5 10 50
Ligand concentration (mM) 100 200 200 200
Ligand buffer 0.8 M AP pH 4.6 0.8 M AP pH 4.6 0.8 M AP pH 4.6 0.8 M AP pH 4.6
Ligand flow (µl min−1) 74.5 54.5 76.7 74.5 71.8
Crystal flow (µl min−1) 5.5 11.6 3.3 5.5 8.2
Mixing injector capillary internal diameter (µm) 50 75 50 50 75
Constriction length (mm) 17.8 36.1 9.3 17.8 36.1
Timing uncertainty (ms) 9.3 1.8 3.0 10.4
Experimental time to collect the data set (min) 50 56 138 250 32