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. 2021 Oct 19;12:692079. doi: 10.3389/fimmu.2021.692079

Figure 6.

Figure 6

Ti-lncRNA signature and immunotherapy response. (A) Associations of the signature risk score with the expression of PDCD1 and CTLA4 and the expanded IGS score. (B) Sub-map analyses of the Ti-lncRNA signature in melanoma patients undergoing blockade therapy of PD-1 and CTLA4. (C) Kaplan–Meier survival curves of OS among four patient groups stratified by the Ti-lncRNA signature, PDCD1 and CTLA-4 expressions, and the expanded IGS scores. lncRNA, long non-coding RNA; Ti-lncRNA, tumor-infiltrating immune-related lncRNA; TCGA, The Cancer Genome Atlas; CAF, cancer-associated fibroblast; TAM, tumor-associated macrophage; IGS, immune gene signature; OS, overall survival.