TABLE 3.

Prevalence of Germline CDKN2A Variants in Patients With PDAC by Ancestry

Patients	No. Germline CDKN2A Variants, n (%)					Study, Year
	Non-Hispanic White	African American	Asian	Native American	Hispanic
FPC	4 (3.3)	–	–	–	–	McWilliams et al, 201140
	13 (3.2)	0 (0)	0 (0)	0 (0)	–	Zhen et al, 201510
	4 (2.2)	0 (0)	–	–	–	Chaffee et al, 201841
	–	–	0 (0)	–	–	Takai et al, 201651
	–	–	0 (0)	–	–	Takai et al, 202052
Nonfamilial PDAC	5 (0.4)	–	–	–	–	McWilliams et al, 201140
	1 (0.1)*	0 (0)†	–	–	–	Shindo et al, 201712
Unselected PDAC	9 (0.3)	0 (0)	0 (0)	–	0 (0)	Hu et al, 20188
	–	3 (1.4)‡	–	1 (9.0)§	4 (3.4)‖	McWilliams et al, 201846

^*0 (0) CDKN2A VUS reported.

^†1 (1.9) CDKN2A VUS reported.

^‡10 (4.5) CDKN2A VUS reported.

^§0 (0) CDKN2A VUS reported.

^‖0 (0) CDKN2A VUS reported.