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. Author manuscript; available in PMC: 2022 Jul 26.
Published in final edited form as: Angew Chem Int Ed Engl. 2021 Jun 28;60(31):17009–17017. doi: 10.1002/anie.202102762

Figure 4. EndoVLISA detects tissue-specific A-to-I editing signatures.

Figure 4.

a) RNA-seq AEI analysis of A-to-I editing in different human tissues from the GTEx project.67 Reproduced from compiled data,31 and values represent mean and SD (brain n = 103 individuals, aorta n = 246, breast n = 219, kidney n = 38, muscle n = 450, pancreas n = 192). b) Purified mRNA (500 ng) from the indicated human tissues was tested using EndoVLISA. Values represent net relative luminescent units (RLU, arbitrary units) calculated by subtracting appropriate blank wells (no RNA) from each set. Data points represent individual values from each well (n = 3 for each sample).