Table 2.
HCC stage, median tumor size, proportion of curative treatment receipt, and OS rate, by sex, age, race or ethnicity, and state in SEER 18 Database
| Characteristic | 2000-2016 (n = 74 610) |
2004-2016 (n = 64 285) | 2000-2016 (n = 74 610) | 2000-2015 (n = 68 876) |
||||
|---|---|---|---|---|---|---|---|---|
| Tumor stagea |
Median tumor size, cm (95% CI)a | Proportion of receiving curative Tx, % (95% CI)a | OS rates |
|||||
| Localized, % (95% CI) | Regional, % (95% CI) | Distant, % (95% CI) | 1-y OS, % (95% CI) | 3-y OS, % (95% CI) | 5-y OS, % (95% CI) | |||
| Overall | 56.8 (56.5 to 57.2) | 29.1 (28.7 to 29.4) | 14.1 (13.8 to 14.4) | 5.0 (5.0 to 5.0) | 27.0 (26.7 to 27.3) | 50.9 (50.6 to 51.3) | 27.6 (27.2 to 27.9) | 19.4 (19.1 to 19.8) |
| Sex | ||||||||
| Male | 55.1 (54.7 to 55.5) | 30.2 (29.8 to 30.6) | 14.7 (14.4 to 15.0) | 5.1 (5.1 to 5.1) | 26.3 (25.9 to 26.6) | 50.1 (49.7 to 50.5) | 26.8 (26.4 to 27.2) | 18.8 (18.4 to 19.1) |
| Female | 62.5 (61.7 to 63.2) | 25.5 (24.9 to 26.2) | 12.0 (11.5 to 12.5) | 4.7 (4.6 to 4.8) | 29.4 (28.8 to 30.1) | 53.5 (52.7 to 54.2) | 30.2 (29.4 to 30.9) | 21.6 (20.9 to 22.3) |
| Age, y | ||||||||
| <50 | 51.9 (50.6 to 53.1) | 30.6 (29.4 to 31.8) | 17.5 (16.6 to 18.5) | 5.8 (5.6 to 6.0) | 32.6 (31.5 to 33.8) | 52.9 (51.7 to 54.2) | 33.2 (32.0 to 34.4) | 26.7 (25.6 to 27.9) |
| 50-64 | 56.8 (56.3 to 57.3) | 29.6 (29.2 to 30.1) | 13.6 (13.2 to 13.9) | 4.5 (4.4 to 4.5) | 28.9 (28.5 to 29.4) | 53.7 (53.2 to 54.3) | 30.9 (30.4 to 31.4) | 23.0 (22.5 to 23.5) |
| ≥65 | 58.0 (57.4 to 58.6) | 28.0 (27.5 to 28.6) | 14.0 (13.6 to 14.4) | 5.6 (5.5 to 5.7) | 23.4 (23.0 to 23.9) | 46.9 (46.3 to 47.5) | 22.0 (21.5 to 22.5) | 13.0 (12.6 to 13.5) |
| Race or ethnicitya | ||||||||
| Non-Hispanic White | 57.0 (56.5 to 57.5) | 28.9 (28.4 to 29.4) | 14.1 (13.7 to 14.5) | 4.8 (4.8 to 4.9) | 28.1 (27.7 to 28.6) | 49.9 (49.4 to 50.4) | 26.6 (26.1 to 27.1) | 18.9 (18.4 to 19.3) |
| Non-Hispanic Black | 52.2 (51.2 to 53.3) | 30.8 (29.8 to 31.7) | 17.0 (16.2 to 17.8) | 5.4 (5.3 to 5.5) | 22.5 (21.7 to 23.3) | 45.7 (44.7 to 46.7) | 22.6 (21.7 to 23.5) | 14.7 (13.9 to 15.6) |
| Non-Hispanic, AI and AN | 54.9 (51.3 to 58.5) | 33.1 (29.8 to 36.6) | 12.0 (9.8 to 14.5) | 5.6 (5.5 to 5.7) | 23.7 (20.9 to 26.6) | 50.2 (46.9 to 53.8) | 27.5 (24.4 to 31.0) | 17.6 (14.8 to 21.0) |
| Non-Hispanic, API | 57.5 (56.6 to 58.4) | 29.4 (28.6 to 30.2) | 13.1 (12.5 to 13.7) | 4.8 (4.5 to 5.1) | 32.5 (31.7 to 33.3) | 56.7 (55.8 to 57.5) | 35.0 (34.1 to 35.9) | 25.7 (24.9 to 26.6) |
| Hispanic | 59.0 (58.1 to 59.9) | 27.9 (27.1 to 28.7) | 13.1 (12.5 to 13.7) | 4.8 (4.7 to 4.8) | 22.3 (21.7 to 23.0) | 51.9 (51.1 to 52.8) | 26.5 (25.7 to 27.4) | 18.0 (17.3 to 18.8) |
| State | ||||||||
| Alaska | 55.6 (45.2 to 65.5) | 30.3 (21.5 to 40.4) | 14.1 (8.0 to 22.6) | 4.6 (3.9 to 5.4) | 40.0 (30.6 to 50.0) | 59.1 (50.2 to 69.6) | 34.2 (25.6 to 45.7) | 25.6 (17.7 to 37.2) |
| California | 57.5 (57.0 to 58.0) | 29.0 (28.5 to 29.5) | 13.5 (13.2 to 13.9) | 5.0 (5.0 to 5.0) | 25.2 (24.7 to 25.6) | 52.8 (52.3 to 53.3) | 28.7 (28.2 to 29.2) | 19.9 (19.4 to 20.4) |
| Connecticut | 57.8 (55.9 to 59.7) | 28.5 (26.8 to 30.2) | 13.7 (12.4 to 15.0) | 4.6 (4.4 to 4.7) | 34.5 (32.8 to 36.3) | 53.5 (51.7 to 55.3) | 29.6 (27.9 to 31.4) | 20.1 (18.5 to 21.9) |
| Georgia | 54.1 (52.8 to 55.4) | 30.5 (29.3 to 31.7) | 15.4 (14.4 to 16.3) | 5.3 (5.1 to 5.4) | 24.0 (22.9 to 25.1) | 46.8 (45.5 to 48.1) | 24.3 (23.1 to 25.5) | 17.5 (16.4 to 18.7) |
| Hawaii | 56.0 (53.5 to 58.4) | 31.1 (28.8 to 33.5) | 12.9 (11.3 to 14.7) | 5.8 (5.5 to 6.0) | 37.9 (35.6 to 40.2) | 52.1 (49.7 to 54.5) | 29.7 (27.5 to 32.1) | 20.5 (18.4 to 22.7) |
| Iowa | 51.0 (48.5 to 53.4) | 34.9 (32.6 to 37.3) | 14.1 (12.5 to 15.9) | 5.1 (4.9 to 5.4) | 23.0 (21.0 to 25.0) | 47.8 (45.5 to 50.3) | 25.5 (23.3 to 27.8) | 18.7 (16.7 to 21.0) |
| Kentucky | 56.3 (54.4 to 58.2) | 28.7 (27.0 to 30.4) | 15.0 (13.7 to 16.4) | 5.2 (5.0 to 5.4) | 30.5 (28.8 to 32.1) | 45.6 (43.8 to 47.4) | 24.6 (23.0 to 26.3) | 17.1 (15.6 to 18.7) |
| Louisiana | 57.3 (55.7 to 58.8) | 27.5 (26.1 to 28.9) | 15.3 (14.1 to 16.4) | 5.3 (5.1 to 5.4) | 24.6 (23.3 to 26.0) | 44.5 (42.9 to 46.1) | 21.8 (20.4 to 23.3) | 16.3 (15.0 to 17.7) |
| Michigan | 54.9 (53.2 to 56.6) | 29.2 (27.7 to 30.8) | 15.9 (14.7 to 17.2) | 5.0 (4.8 to 5.2) | 30.6 (29.0 to 32.1) | 47.1 (45.4 to 48.8) | 26.1 (24.6 to 27.7) | 18.5 (17.1 to 20.0) |
| New Jersey | 57.4 (56.1 to 58.7) | 26.3 (25.2 to 27.4) | 16.3 (15.3 to 17.3) | 5.0 (4.9 to 5.1) | 31.0 (29.9 to 32.1) | 50.2 (49.1 to 51.5) | 27.7 (26.6 to 28.8) | 20.5 (19.4 to 21.6) |
| New Mexico | 62.1 (59.7 to 64.4) | 22.5 (20.5 to 24.6) | 15.5 (13.7 to 17.3) | 5.2 (5.0 to 5.4) | 20.1 (18.3 to 21.9) | 47.5 (45.3 to 49.9) | 23.9 (21.8 to 26.1) | 16.7 (14.8 to 18.8) |
| Utah | 57.8 (54.7 to 60.8) | 29.9 (27.2 to 32.8) | 12.3 (10.4 to 14.5) | 4.9 (4.6 to 5.2) | 28.3 (25.7 to 31.1) | 49.7 (46.8 to 52.8) | 28.0 (25.3 to 31.1) | 20.0 (17.4 to 23.0) |
| Washington | 55.6 (54.1 to 57.1) | 32.9 (31.5 to 34.3) | 11.5 (10.6 to 12.5) | 4.4 (4.3 to 4.6) | 31.6 (30.2 to 32.9) | 55.0 (53.5 to 56.4) | 30.7 (29.3 to 32.2) | 21.8 (20.4 to 23.2) |
a
Percents were calculated after excluding missing data for race or ethnicity (0.2%), tumor size (17.3%), tumor stage (8.9%), and treatment modality (0.9%). AI and AN = American Indian and Alaska Native; API = Asian and Pacific Islander; CI = confidence interval; HCC = hepatocellular carcinoma; OS = overall survival; SEER = Surveillance, Epidemiology, and End Results; Tx = treatment.