Table 2:

Adjusted odds ratios for hospitalization, intensive care unit admission, and death among reported COVID-19 cases^*

Variable	Hospitalization OR (95% CI)	ICU admission OR (95% CI)	Death OR (95% CI)
VOC status
Non-VOC	Ref.	Ref.	Ref.
Probable Delta variant	2.08 (1.78–2.40)	3.35 (2.60–4.31)	2.33 (1.54–3.31)
N501Y+ variant	1.52 (1.42–1.63)	1.89 (1.67–2.17)	1.51 (1.30–1.78)
Sex, male	1.29 (1.23–1.36)	1.60 (1.48–1.75)	1.67 (1.50–1.85)
Age, yr (per 10-year increase)	2.07 (2.04–2.10)	1.96 (1.91–2.01)	3.46 (3.32–3.59)
Vaccination status
Nonvaccinated	Ref.	Ref.	Ref.
Partially vaccinated	0.42 (0.40–0.44)	0.28 (0.25–0.30)	0.09 (0.07–0.10)
Fully vaccinated	0.31 (0.23–0.43)	0.15 (0.04–0.30)	0.21 (0.10–0.35)
Comorbidity†	2.76 (2.59–2.95)	2.58 (2.28–2.90)	2.40 (2.08–2.71)
Pregnant	6.26 (4.56–8.43)	6.85 (3.59–10.80)	–
Series week‡	0.99 (0.99–1.00)	0.98 (0.97–0.99)	0.96 (0.95–0.98)

Note: CI = confidence interval, ICU = intensive care unit, OR = odds ratio, VOC = variant of concern.

^*We treated health units as random effects in models.

^†Comorbidities include 1 or more of asthma, chronic obstructive pulmonary disease, hematological disease, liver disease, cardiac disease, diabetes, immune compromise, renal disease, neurologic disease, malignancy, or obesity.

^‡Week from Feb. 7 to June 27, 2021, modelled as a continuous variable.