FIGURE 3.

Septal and Peripheral PG synthesis components. (Top) Organisation of FtsZ Ring (dark purple) and MapZ ring (light purple) as well as septal (blue) and periphery (orange) PG synthases represented across the longitudinal and transverse plan of the pneumococcal cell. (Bottom) Schematic representation of the spatial and functional separation of divisome machinery between septal (blue box) and peripheral (orange box) machinery located in the inner and outer PG synthesis rings at opposite edges of the midcell annular disk. The organisation of the outer peripheral ring is unknown and may contain additional components, thus denoted here as “other putative peripheral components in outer ring”.