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The Proposed Immunomodulatory Effects of Macrolides on T-Cell function. Macrolide antibiotics (MA) directly influence T-cell function by attenuating cytokine secretion. Contradictory evidence (indicated by question marks) exists regarding the effect of macrolides on T-cell apoptosis, proliferation, and if, via DC attenuation, Macrolides can indirectly affect T-cell function.
