Table 3. Symptom score changes by condition.

Symptom score by condition		Immunotherapy group	Drug only group	p-value†
Bronchial asthma		n = 51	n = 17
	−3	0 (0)	0 (0)
	−2	0 (0)	0 (0)
	−1	0 (0)	3 (17.65)
	0	1 (1.96)	5 (29.41)
	1	8 (15.69)	5 (29.41)
	2	42 (82.35)	4 (23.53)
	3	0 (0)	0 (0)
	Mean±SD	1.88±0.45	0.59±1.06	<0.001
	Median (range)	2 (0–2)	1 (−1 to 2)
Allergic rhinitis		n = 51	n = 17
	−3	0 (0)	0 (0)
	−2	0 (0)	1 (5.88)
	−1	0 (0)	2 (11.76)
	0	11 (21.57)	8 (47.06)
	1	20 (39.22)	4 (23.53)
	2	20 (39.22)	2 (23.53)
	3	0 (0)	0 (0)
	Mean±SD	1.18±0.45	0.24±1.06	0.001
	Median (range)	2 (0–2)	0 (−2 to 2)
Upper respiratory tract infection		n = 51	n = 17
	−3	0 (0)	0 (0)
	−2	0 (0)	0 (0)
	−1	0 (0)	0 (0)
	0	2/51 (3.92)	8 (47.06)
	1	10 (19.61)	6 (35.29)
	2	38 (74.51)	3 (0)
	3	1 (1.96)	0 (0)
	Mean±SD	1.75±0.56	0.71±0.77	<0.001
	Median (range)	2 (0–3)	1 (0–2)

SD, standard deviation.

^†Wilcoxon rank-sum test comparing change in immunotherapy group to drug only group.

Score: −3, much worse; −2, a good deal worse; −1, slightly worse; 0, more or less the same; +1, slightly better; +2, a good deal better; +3, much better.