Table 4.

Changes of serum IGF-1 before and after treatment of ISS with different doses of rhGH (n, $\overline{x}$ ± s, ng/mL).

Group	Number of cases	Before treatment	6 months after treatment	12 months after treatment	24 months after treatment
Low-dose group	59	129.85 ± 81.64	262.67 ± 102.55∗	384.40 ± 98.36∗	447.53 ± 77.65∗
High-dose group	44	131.09 ± 80.31	295.43 ± 104.68∗	357.15 ± 80.54∗	461.62 ± 73.21∗
t value		0.076	1.589	1.500	0.933
P value		0.938	0.115	0.136	0.352

Note. Compared with that before treatment, ^∗P < 0.05.