Table 1.
Characteristics of the Study Population by Latent Tuberculosis Infection
| Peru | Uganda | Total | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Characteristics | No LTBI (n = 27) | LTBIa (n = 42) | P b | No LTBI (n = 64) | LTBI (n = 71) | P b | No LTBI (n = 91) | LTBI (n = 113) | P b |
| Age, years | 51 (43–66) | 54 (47–60) | .777 | 57 (53–62) | 57 (52–62) | .949 | 55 (49–64) | 56 (51–62) | .829 |
| Male sex at birth, n (%) | 15 (56) | 19 (45) | .403 | 23 (36) | 24 (34) | .795 | 38 (42) | 43 (38) | .519 |
| Hypertension,c n (%) | 4 (15) | 7 (17) | .838 | 54 (84) | 64 (90) | .313 | 58 (64) | 71 (63) | .894 |
| Diabetes mellitus,c n (%) | 4 (15) | 11 (26) | .264 | 20 (31) | 20 (28) | .695 | 24 (26) | 31 (27) | .865 |
| Hyperlipidemia,c n (%) | 9 (33) | 11 (26) | .523 | 7 (11) | 15 (21) | .109 | 16 (18) | 26 (23) | .341 |
| Current smoking, n (%) | 1 (4) | 4 (10) | .641 | 1 (2) | 5 (7) | .212 | 2 (2) | 9 (8) | .116 |
| Systolic BP, mm Hg | 116 (105–130) | 120 (110–130) | .877 | 140 (122–160) | 137 (121–162) | .984 | 130 (116–150) | 128 (115–145) | .519 |
| Diastolic BP, mm Hg | 70 (70–80) | 78 (70–80) | .488 | 81 (72–88) | 79 (70–93) | .899 | 79 (70–87) | 79 (70–88) | .989 |
| BMI, kg/m2 | 26.4 (24.3–27.9) | 27.2 (25.9–29.1) | .041 | 28.1 (25.2–32.7) | 29.9 (24.9–33.5) | .600 | 27.3 (24.5–30.9) | 28 (25.6–32) | .248 |
| Total cholesterol, mg/dL | 188 (164–211) | 201 (179–222) | .127 | 205 (180–237) | 191 (167–226) | .067 | 198 (175–233) | 193 (173–224) | .415 |
| LDL cholesterol, mg/dL | 105 (92–131) | 114 (102–134) | .379 | 130 (111–166) | 128 (106–149) | .179 | 128 (102–160) | 123 (103–143) | .279 |
| HDL cholesterol, mg/dL | 46 (38–53) | 43 (37–47) | .203 | 54 (45–68) | 53 (43–66) | .671 | 49 (43–60) | 47 (39–61) | .211 |
| ASCVD score | 4.2 (0.7–8.2) | 5.4 (1.7–9.8) | .522 | 6.4 (3.2–11.8) | 7.9 (4.1–12.7) | .428 | 6.1 (2.8–10.8) | 7.1 (3.2–11.7) | .533 |
| Creatinine, mg/dL | 0.73 (0.58–0.94) | 0.64 (0.57–0.74) | .094 | 0.79 (0.63–0.92) | 0.77 (0.65–0.93) | .636 | 0.78 (0.62–0.92) | 0.73 (0.6–0.88) | .365 |
Numeric variables are presented as median with interquartile ranges in parentheses. Categorical variables are presented as number of subjects with percentages in parentheses. Abbreviations: ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LTBI, latent tuberculosis infection.
aLTBI defined by a positive QuantiFERON-TB test.
b P values derived by Mann-Whitney-Wilcoxon test for numeric variables. P values derived by chi-square or Fisher’s exact test for categorical variables. Fisher’s exact test was used when a cell had 5 events or less.
cHistory of diabetes mellitus, hypertension, and hyperlipidemia were defined by self-report and verified in available medical records.