Table 2.
Coronary Atherosclerosis Parameters Characterized in Computed Tomography Angiography
| Peru | Uganda | Total | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Characteristics | No LTBI (n = 27) | LTBIa (n = 42) | P b | No LTBI (n = 64) | LTBI (n = 71) | P b | No LTBI (n = 91) | LTBI (n = 113) | P b |
| CAD (any plaque), n (%) | 9 (33) | 16 (38) | .799 | 13 (20) | 17 (24) | .612 | 22 (24) | 33 (29) | .421 |
| CAD-RADS score | 0 (0–1) | 0 (0–1) | .463 | 0 (0–0) | 0 (0–0) | .626 | 0 (0–0) | 0 (0–1) | .366 |
| CAD-RADS, n (%) | .705 | .099 | .104 | ||||||
| 0 = no plaque | 18 (67) | 26 (62) | 51 (79) | 54 (76) | 69 (76) | 80 (71) | |||
| 1 = 1–24% stenosis | 7 (26) | 9 (21) | 2 (3) | 5 (7) | 9 (10) | 13 (12) | |||
| 2 = 25–49% stenosis | 2 (7) | 4 (10) | 8 (12) | 5 (7) | 10 (11) | 9 (8) | |||
| 3 = 50–69% stenosis | 0 | 3 (7) | 1 (2) | 7 (10) | 1 (1) | 10 (9) | |||
| 4 = 70–99% stenosis | 0 | 1 (2) | 1 (2) | 0 | 1 (1) | 1 (1) | |||
| 5 = total occlusion | 0 | 0 | 1 (2) | 0 | 1 (1) | 0 | |||
| Obstructive CAD, n (%) | 0 | 4 (10) | .150 | 3 (5) | 7 (10) | .332 | 3 (3) | 11 (9) | .095 |
| SIS (all; n = 204) | 0 (0–2) | 0 (0–2) | .612 | 0 (0–0) | 0 (0–0) | .739 | 0 (0–0) | 0 (0–1) | .495 |
| SIS (if SIS >0; n = 55) | 3 (2–3) | 3 (2–6) | .623 | 2 (1–5) | 2 (1–2) | .227 | 2 (2–3) | 2 (1–3) | .536 |
| SSS (all; n = 204) | 0 (0–2) | 0 (0–2) | .567 | 0 (0–0) | 0 (0–0) | .744 | 0 (0–0) | 0 (0–1) | .482 |
| SSS (if SSS >0; n = 55) | 3 (2–3) | 4 (2–8) | .452 | 3 (2–8) | 2 (2–4) | .224 | 3 (2–5) | 3 (2–6) | .617 |
| CAC (all; n = 204) | 0 (0–22) | 0 (0–15) | .970 | 0 (0–0) | 0 (0–0) | .658 | 0 (0–0) | 0 (0–1) | .619 |
| CAC (if CAC >0; n = 54) | 26 (22–163) | 55 (15–135) | .899 | 76 (14–593) | 33 (3–87) | .194 | 59 (16–191) | 42 (12–105) | .301 |
Numeric variables are presented as median with interquartile ranges in parentheses. Categorical variables are presented as number of subjects with percentages in parentheses. Abbreviations: CAC, coronary artery calcium score; CAD, coronary artery disease; CAD-RADS, Coronary Artery Disease–Reporting Data System; LTBI, latent tuberculosis infection; SIS, segment involvement score; SSS, segment stenosis score.
aLTBI defined by a positive QuantiFERON-TB test.
b P values derived by Mann-Whitney-Wilcoxon test for numeric variables. P values derived by chi-square or Fisher’s exact test for categorical variables. Fisher’s exact test was used when a cell had 5 events or less.