Figure 4.

Plasma chemokines are biomarkers of individual treatment outcomes in active tuberculosis (TB) disease. A, Receiver operator characteristic (ROC) analysis to estimate the sensitivity, specificity, and AUC was performed using chemokines to estimate the capacity of chemokines to distinguish TB recurrence vs recurrence-free cure. Only the chemokines that showed significant P values in discrimination are shown. B, ROC analysis to estimate the sensitivity, specificity, and AUC was performed using chemokines to estimate the capacity of chemokines to distinguish treatment failure vs cure. Only the chemokines that showed significant P values in discrimination are shown. C, ROC analysis to estimate the sensitivity, specificity, and AUC was performed using chemokines to estimate the capacity of chemokines to distinguish mortality during TB treatment vs survival. Only the chemokines that showed significant P values in discrimination are shown. Abbreviation: AUC, area under the curve.