Table 1.
Clinical characteristics of the four groups.
| Characteristics | Non-severe COVID-19 |
Severe COVID-19 |
P value | ||||
|---|---|---|---|---|---|---|---|
| Non-CVD (n = 90) | CVD (n = 22) | P value | Non-CVD (n = 40) | CVD (n = 28) | P value | ||
| Age, mean ± SD years | 47.92 ± 14.44 | 61.55 ± 12.38 | 0.236 | 61.90 ± 15.87 | 64.78 ± 10.70 | 0.012 | 0.393 |
| Male, n (%) | 45 (50.0) | 14 (63.6) | 0.341 | 19 (47.4) | 17 (60.7) | 0.330 | 1.000 |
| BMI (kg/m2) | 25.01 ± 3.37 | 24.46 ± 2.88 | 0.465 | 24.62 ± 3.41 | 24.25 ± 2.76 | 0.621 | 0.561 |
| Drinking history, n (%) | 24 (26.7) | 7 (31.8) | 0.606 | 16 (40.0) | 8 (28.6) | 0.441 | 0.318 |
| Smoking history, n (%) | 18 (20.0) | 5 (22.7) | 0.773 | 13 (32.5) | 7 (25.0) | 0.594 | 0.208 |
| Hypertension, n (%) | – | 19 (86.4) | – | – | 23 (82.1) | – | 0.011 |
| Diabetes Mellitus, n (%) | – | 4 (18.2) | – | – | 12 (42.9) | – | 0.002 |
| CAD, n (%) | – | 4 (18.2) | – | – | 9 (32.1) | – | 0.018 |
| HF, n (%) | – | 3 (13.6) | – | – | 7 (25.0) | – | 0.036 |
| Systolic blood pressure at admission (mmHg) | 123.77 ± 10.08 | 128.41 ± 10.91 | 0.311 | 125.35 ± 14.89 | 129.43 ± 12.78 | 0.588 | 0.007 |
| Diastolic blood pressure at admission (mmHg) | 76.33 ± 7.57 | 79.81 ± 9.85 | 0.113 | 76.50 ± 9.79 | 79.29 ± 9.08 | 0.721 | 0.122 |
| Clinical manifestation | |||||||
| Fever, n (%) | 71 (78.9) | 15 (68.2) | 0.397 | 33 (82.5) | 26 (92.9) | 0.003 | 0.122 |
| Cough, n (%) | 56 (62.2) | 14 (63.6) | 0.902 | 26 (65.0) | 19 (67.9) | 0.806 | 0.635 |
| Dyspnea, n (%) | 4 (4.4) | 1 (4.5) | 1.000 | 8 (20.0) | 5 (17.9) | 0.825 | 0.004 |
| Fatigue, n (%) | 18 (20.0) | 7 (31.8) | 0.259 | 14 (35.0) | 10 (35.7) | 0.952 | 0.083 |
Date are presented as mean ± SD,M [P25, P75] or number (percentage). CAD: coronary heart disease; HF: heart failure.