Table 2.
Laboratory test results in the four groups.
| Laboratory findings | Non-severe COVID-19 |
Severe COVID-19 |
P value | ||||
|---|---|---|---|---|---|---|---|
| Non-CVD (n = 90) | CVD (n = 22) | P value | Non-CVD (n = 40) | CVD (n = 28) | P value | ||
| WBC (×109) | 8.19 (6.02, 9.66) | 9.73 (7.25, 10.75) | 0.010 | 13.75 (9.00, 16.35) | 12.56 (6.20, 16.86) | 0.404 | <0.001 |
| IL-6 (pg/ml) | 5.66 (2.88, 6.38) | 8.11 (5.35, 9.86) | 0.003 | 266.49 (18.87, 74.64) | 79.10 (22.70, 93.99) | 0.307 | <0.001 |
| CRP (mg/L) | 28.50 (6.40, 34.35) | 52.19 (27.95, 81.43) | 0.001 | 86.82 (28.43, 131.23) | 106.10 (46.38, 141.58) | 0.140 | <0.001 |
| Hb (g/L) | 126.61 (115.00, 140.25) | 117.27 (103.75, 132.00) | 0.027 | 13.33 (94.25, 129.25) | 116.29 (108.25, 128.00) | 0.566 | 0.002 |
| D-dimer (μg/ml) | 0.69 (0.30, 0.73) | 1.37 (0.36,1.40) | 0.011 | 1.77 (0.62, 2.00) | 1.36 (0.65, 1.88) | 0.779 | <0.001 |
| CK (IU/L) | 112.51 (47.00,123.25) | 98.41 (39.00, 145.25) | 0.613 | 288.90 (39.00, 217.75) | 291.46 (31.25, 200.50) | 0.474 | 0.287 |
| CKMB (IU/L) | 12.23 (8.00, 14.00) | 9.64 (6.75, 11.75) | 0.091 | 18.80 (9.25, 17.00) | 19.32 (7.50, 22.50) | 0.750 | 0.001 |
| ALT (U/L) | 84.54 (30.75, 107.5) | 72.95 (33.50, 79.50) | 0.575 | 155.75 (45.75, 124.50) | 106.32 (35.25, 134.75) | 0.672 | 0.044 |
| AST (U/L) | 44.54 (25.00, 57.00) | 44.95 (26.50, 46.75) | 0.985 | 170.58 (36.25, 93.75) | 74.64 (35.25, 82.75) | 0.774 | <0.001 |
| SCR (μml/L) | 71.23 (56.13,83.20) | 79.74 (65.80, 81.18) | 0.075 | 92.53 (57.13, 97.88) | 106.71 (69.10, 108.58) | 0.100 | 0.021 |
| NT-proBNP (pg/ml) | 135.88 (62.50, 105.50) | 514.64 (72.75, 493.50) | 0.009 | 1062.30 (118.00, 697.25) | 1323.59 (227.50, 1711.50) | 0.017 | <0.001 |
| FBG (mmol/L) | 6.56 (5.07, 7.31) | 9.03 (5.71, 10.68) | 0.009 | 7.72 (5.87, 9.15) | 7.76 (5.17, 9.43) | 0.529 | 0.034 |
| cTnI (pg/ml) | 0.36 (0.01, 0.05) | 0.20 (0.01, 0.01) | 0.053 | 6.06 (0.01, 0.24) | 8.92 (0.01, 1.00) | 0.843 | 0.072 |
Date are presented as M (P25, P75). WBC: white blood cell; IL-6: interleukin-6; CRP: C-reactive protein; Hb: hemoglobin; CK: creatine kinase; CKMB: creatine kinase isoenzyme; ALT: alanine aminotransferase; AST: aspartate aminotransferase; SCR: serum creatinine; NT-proBNP: N-terminal pro hormone B-type natriuretic peptide; FBG: fasting blood glucose; cTnI: cardiac troponin I.