Table 1:
Characteristics of P/LP BRCA1, BRCA2, PALB2, and ATM carriers without a family history of PDAC who underwent EUS for PDAC surveillance.
| N = 64 | ||
|---|---|---|
| Age at first EUS, median, IQR | 62 | 53–67 |
| Female | 46 | 72% |
| Race | ||
| White | 61 | 95% |
| Non-white | 2 | 3% |
| Not reported | 1 | 2% |
| Ashkenazi Jewish ancestry | 21 | 33% |
| P/LP gene variant | ||
| BRCA1 | 12 | 19% |
| BRCA2 | 47 | 73% |
| PALB2 | 2 | 3% |
| ATM | 3 | 5% |
| Smoking | ||
| Never | 48 | 75% |
| Former | 13 | 20% |
| Current | 3 | 5% |
| Alcohol use | 47 | 73% |
| Prior pancreatitis | 3 | 5% |
| Type II DM | 6 | 9% |
| Personal history of cancer | ||
| Any cancer | 43 | 67% |
| Breast | 34 | 53% |
| Ovarian | 1 | 2% |
| Prostate | 2 | 3% |
| Family history of cancer | ||
| Any cancer | 64 | 100% |
| Breast | 57 | 89% |
| Ovarian | 21 | 33% |
| Prostate | 23 | 36% |