Phenotype	Score of 0 (absent)	Score of 1 (present)	Score of 2 (severe)
Activity	Typically responsive	Minimally responsive	Nonresponsive
Hindlimb clasping	Legs typically spread	One leg held against body	Both legs held against body
Tremor	No tremor	Intermittent tremor	Continuous tremor
Breathing	Typical breathing	Hyperventilation or pauses in breathing	Gasps or panting
Coat condition	Typically groomed fur	Fur poorly groomed on close inspection (during handling)	Fur obviously poorly groomed (noticed immediately when cage is opened)
Hunch	No hunch	Hunch present on palpation	Hunch visualized without palpation
Gait	Typical gait	Wide stance or waddling gait	Uncoordinated or “hopping” gait