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. 2021 Oct 20;12:682454. doi: 10.3389/fpsyt.2021.682454

Figure 1.

Figure 1

Overview of groupwise subject gut microbiome ecological diversity and differentially enriched gut microbiota that are most prevalent in ASD group subjects, followed by healthy controls and first-degree relative controls, respectively. (A) Groupwise comparison of alpha diversity determined via Shannon index in all groups. (B) Alpha diversity via the Shannon index displays significant inverse correlation with ADOS overall score. (C) PCoA of species after filtering (Bray-Curtis) with 95% confidence ellipses. ASD microbiota showed (D) a lower abundance of Akkermansia but a higher abundance of (E) enterobacteriaceae, (F) phyllobacterium, (G) E. Shigella, and (H) E. coli when compared to first-degree relative controls and healthy controls.