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. 2021 May 20;28(11):3077–3091. doi: 10.1038/s41418-021-00803-1

Fig. 2. TRIM26 enhances TLRs-induced NF-κB and MAPK signaling.

Fig. 2

A Immunoblot analysis of phosphorylated and total IKKα/β, p65, ERK, JNK, and p38 in peritoneal macrophages from Trim26+/+ and Trim26–/– mice stimulated with LPS for indicated times. B–D Immunoblot analysis of phosphorylated and total IKKα/β, p65, ERK, JNK, and p38 in peritoneal macrophages from Trim26+/+ and Trim26–/– mice stimulated with Pam3CSK4(1 µg/ml), Poly(I:C) (20 µg/ml), or TNF-α (20 ng/ml) for indicated times. Similar results were obtained in three independent experiments.