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. 2021 Feb 8;42(11):1821–1833. doi: 10.1038/s41401-020-00601-4

Fig. 6. The functions and metabolites of the gut microbiota were altered after berberine treatment.

Fig. 6

a Principal component analysis of the enrichment of KEGG pathways. n = 12 (GH); n = 14 (GI, GIBBR). b Pathway enrichment analysis of significantly altered Kyoto Encyclopedia of Genes and Genomes orthologies after berberine treatment. n = 12 (GH); n = 14 (GI, GIBBR). c Enrichment of pathways involved in propanoate and butanoate. n = 12 (GH); n = 14 (GI, GIBBR). d Fecal concentrations of SCFAs. n = 6 (GH); n = 8 (GI, GIBBR). *P < 0.05, **P < 0.01, ****P < 0.0001.