Table 1.
Serum and liver tissue biochemical analysis of BDL rats.
| Sham (n = 6) | BDL-NS (n = 6) | BDL-PPZ (n = 6) | |
|---|---|---|---|
| Serum AST (U· L−1) | 167.71 ± 41.43 | 711.67 ± 119.18## | 349.33 ± 204.71** |
| Serum ALT (U· L−1) | 27.25 ± 6.34 | 100.33 ± 28.06## | 50.00 ± 24.75** |
| Serum ALP (U· L−1) | 188.25 ± 62.37 | 391.33 ± 74.07## | 268.17 ± 125.01 |
| Serum GGT (U· L−1) | / | 52.50 ± 16.02## | 30.17 ± 36.69 |
| Serum CHO (mmol· L−1) | 1.50 ± 0.33 | 3.57 ± 0.09## | 3.28 ± 0.67 |
| Serum LDL (mmol· L−1) | 0.23 ± 0.07 | 2.23 ± 0.18## | 1.57 ± 0.93 |
| Serum HDL (mmol· L−1) | 0.65 ± 0.09 | 0.61 ± 0.04 | 0.71 ± 0.13 |
| Serum TG (mmol· L−1) | 0.46 ± 0.02 | 0.94 ± 0.13## | 0.89 ± 0.55 |
| Serum TBA (μmol· L−1) | 6.33 ± 1.43 | 255.23 ± 50.81## | 95.45 ± 89.95** |
| Serum TBiL (μmol· L−1) | 0.55 ± 0.52 | 168.60 ± 22.63## | 69.35 ± 70.75* |
| Liver tissue TBA (nmol· mg−1) | 67.8 ± 45.3 | 184.25 ± 75.50## | 90.41 ± 50.60* |
Values are presented as the mean ± SD (n = 6 per group).
AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, CHO cholesterol, LDL low-density lipoprotein cholesterol, HDL high-density lipoprotein cholesterol, TG triglyceride, TBA total bile acid, TBiL total bilirubin.
##P < 0.01 vs. the sham group; *P < 0.05, **P < 0.01, vs. the BDL-NS group.