Table 2.
The side effects of Sputnik V COVID-19 vaccine after first and second dose.
| First dose (N = 2194) N (%) |
Second dose (N = 1042) N (%) |
Total (N = 3236) N (%) |
P value | |
|---|---|---|---|---|
| Local side effects on the injection site | ||||
| Pain | 1278 (58.2) | 564 (54.1) | 1842 (56.9) | 0.028 |
| Swelling | 138 (6.3) | 89 (8.5) | 227 (7) | 0.022 |
| Redness | 125 (5.7) | 68 (6.5) | 193 (6) | 0.382 |
| Systemic side effects | ||||
| Fever | 801 (36.5) | 248 (23.8) | 1049 (32.4) | < 0.0001 |
| Chilling | 727 (33.1) | 237 (22.7) | 964 (29.8) | < 0.0001 |
| Headache | 835 (38.1) | 321 (30.8) | 1156 (35.7) | < 0.0001 |
| Dizzying | 318 (14.5) | 129(12.4) | 447 (13.8) | 0.114 |
| Body pain | 1067 (48.6) | 396 (38) | 1463 (45.2) | < 0.0001 |
| Fatigue | 1189 (54.2) | 459 (44) | 1648 (50.9) | < 0.0001 |
| Weakness | 1023 (46.6) | 397 (38.1) | 1420 (43.9) | < 0.0001 |
| Nausea | 201 (9.2) | 68 (6.5) | 296 (8.3) | 0.012 |
| Vomiting | 30 (1.4) | 13 (1.2) | 43 (1.3) | 0.870 |
| Diarrhea | 113 (5.2) | 50 (4.8) | 163 (5) | 0.731 |
| Constipation | 1 (0.04) | 2 (0.2) | 3 (0.1) | 0.244 |
| Joint pain | 707 (32.2) | 275 (26.4) | 982 (30.3) | 0.001 |
| Vasovagal syncope | 15 (0.7) | 6 (0.6) | 21 (0.60) | 0.818 |
| Anaphylaxis shock | 4 (0.2) | 0 | 4 (0.1) | 0.312 |
| Rash | 47 (2.1) | 26 (2.5) | 73 (2.3) | 0.528 |
| Depression | 143 (6.5) | 54 (5.2) | 197 (6.1) | 0.157 |
| Drowsiness | 470 (21.4) | 187 (17.9) | 657 (20.3) | 0.022 |
P value < 0.05 showed by boldface.