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. 2021 Oct 20;9:740455. doi: 10.3389/fcell.2021.740455

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Copyright © 2021 Ren, Wang, Gu, Ma, Zhu, Cai and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Independent prognostic analysis and nomogram of the 8-lncRNA prognostic signature. (A) Univariate Cox regression of the TCGA cohort. (B) Multivariate Cox regression of the TCGA cohort based on overall survival. Age (>65 vs. ≤65), gender (male vs. female), stage (III/IV vs. I/II), T (III/IV vs. I/II), M (I vs. 0), N (I/II vs. 0), KRAS (mutation vs. wild), TP53 (mutation vs. wild), BRAF (mutation vs. wild), POLE (mutation vs. wild), and risk (low-risk vs. high-risk). (C) Nomogram of the TCGA cohort based on overall survival (M was not included in the nomogram due to only 20 patients with M1). (D) Calibration curve of the TCGA cohort based on overall survival at 1, 2, and 3 years.