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. 2021 Oct 20;13:751913. doi: 10.3389/fnagi.2021.751913

FIGURE 2.

FIGURE 2

MAMPH-induced conditioned taste aversion tested for behavior using NMDA or saline injections. Mean (± SEM) intake volume of 0.1% saccharin solution for three sessions (with 1 mg/kg of intraperitoneally injected MAMPH) across the control (n = 19), MAMPH (n = 14), PrL (+)/MAMPH (n = 12), and PrL(–)/MAMPH groups (n = 20). PrL(+): Injection of a low concentration of NMDA to excite the PrL neurons; PrL(–): Injection of a high concentration of NMDA to destroy the PrL neurons. Differences in the intake volumes of 0.1% saccharin solution among all groups in each session were analyzed by one-way ANOVA, followed by Tukey’s post hoc test if a significant difference was appeared among groups. *p < 0.05 indicates significant differences compared with the control group; #p < 0.05 indicates significant differences compared with the MAMPH group.